Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs.

Molecular and cellular biology - 1 Sept 2007

Harrington Jill M, Kolodner Richard D

Abstract excerpt

DNA mismatch repair is thought to act through two subpathways involving the recognition of base-base and insertion/deletion mispairs by the Msh2-Msh6 heterodimer and the recognition of insertion/deletion mispairs by the Msh2-Msh3 heterodimer. Here, through genetic and biochemical approaches, we describe a previously unidentified role of the Msh2-Msh3 heterodimer in the recognition of base-base mispairs and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Base Pair Mismatch
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Fungal

Share to Fungal Proteins

Share to MutS Homolog 2 Protein

Share to MutS Homolog 3 Protein

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17636021
DOI: 10.1128/MCB.00855-07
PMCID: PMC2099603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs.PMID 17636021Read ↗

Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex.Semantic proximity Read ↗

A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition.Semantic proximity Read ↗

Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP.Semantic proximity Read ↗

Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.Semantic proximity Read ↗

ATP binding and hydrolysis by Saccharomyces cerevisiae Msh2-Msh3 are differentially modulated by mismatch and double-strand break repair DNA substrates.Semantic proximity Read ↗

Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps.Semantic proximity Read ↗

Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition.Semantic proximity Read ↗

Binding of insertion/deletion DNA mismatches by the heterodimer of yeast mismatch repair proteins MSH2 and MSH3Semantic proximity Read ↗

Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivoSemantic proximity Read ↗

Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability.Semantic proximity Read ↗

Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I.Semantic proximity Read ↗

Physical interaction between components of DNA mismatch repair and nucleotide excision repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.