Article
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
Genes & development - 15 Feb 1996
Marsischky G T, Filosi N, Kane M F, Kolodner R
Abstract excerpt
Saccharomyces cerevisiae encodes six genes, MSH1-6, which encode proteins related to the bacterial MutS protein. In this study the role of MSH2, MSH3, and MSH6 in mismatch repair has been examined by measuring the rate of accumulating mutations and mutation spectrum in strains containing differen...
Topics
- Adenosine Triphosphatases
- Alleles
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- DNA Primers
- DNA Repair
- DNA, Fungal
- DNA-Binding Proteins
- Databases, Factual
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli Proteins
- Fungal Proteins
- Genes, Fungal
- Models, Genetic
- Molecular Sequence Data
- MutS DNA Mismatch-Binding Protein
- MutS Homolog 2 Protein