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Article

Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development.

Molecular and cellular biology - 1 Sept 2007

Ursini-Siegel Josie, Rajput Ashish B, Lu Huiling, Sanguin-Gendreau Virginie, Zuo Dongmei, Papavasiliou Vasilios, Lavoie Cynthia, Turpin Jason, Cianflone Katherine, Huntsman David G, Muller William J

Abstract excerpt

Tumor cells utilize glucose as a primary energy source and require ongoing lipid biosynthesis for growth. Expression of DecR1, an auxiliary enzyme in the fatty acid beta-oxidation pathway, is significantly diminished in numerous spontaneous mammary tumor models and in primary human breast cancer....

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Share to Cell Line, Transformed
Share to Fatty Acids
Share to Fluorescent Antibody Technique, Direct

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammary Glands, Animal

Share to Mammary Neoplasms, Experimental

Share to Neoplasm Transplantation

Share to Receptor, ErbB-2

Share to Transplantation, Homologous

Source

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Identifiers

PMID: 17636013
DOI: 10.1128/MCB.00686-07
PMCID: PMC2099621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17636013-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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