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Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532

4 Jul 2014

Abstract excerpt

BACKGROUND: Considerable progress has been made to understand the association between lifestyle and diet in cancer initiation and promotion. Because excessive glucose consumption is a key metabolic hallmark of cancer cells, glucose restriction (GR) decreases the proliferation, and promotes the differentiation and transformation of cancer cells to quiescent cells. The immortality of cancerous cells is largely...

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Share to Endoplasmic Reticulum Stress and Disease
Share to Metabolism, Diabetes, and Cancer
Share to Telomeres, Telomerase, and Senescence

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PMID: 25089119
DOI: 10.1186/1475-2867-14-60

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