Article
Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors.
The Journal of biological chemistry - 5 Oct 2007
Thompson Dawn, Pusch Margareta, Whistler Jennifer L
Abstract excerpt
After activation, most G protein-coupled receptors (GPCRs) are regulated by a cascade of events involving desensitization and endocytosis. Internalized receptors can then be recycled to the plasma membrane, retained in an endosomal compartment, or targeted for degradation. The GPCR-associated sor...
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