Article
Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus.
Journal of virology - 1 May 1990
Aldovini A, Young R A
Abstract excerpt
To identify RNA and protein sequences involved in packaging of human immunodeficiency virus type 1 (HIV-1), various mutations were introduced into the viral genome. Portions of the human immunodeficiency virus type 1 genome between the first splice donor site and the gag initiation codon were del...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- DNA-Binding Proteins
- Genes, Viral
- HIV-1
- Metalloproteins
- Microscopy, Electron
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
- RNA, Viral
- Transfection
- Viral Proteins
- Virulence
- Zinc