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Article

Characterization of human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid protein at a putative HIV-1 protease cleavage site.

Virology - 25 Oct 2006

Thomas James A, Shulenin Sergey, Coren Lori V, Bosche William J, Gagliardi Tracy D, Gorelick Robert J, Oroszlan Stephen

Abstract excerpt

The HIV-1 nucleocapsid protein (NC) has been hypothesized to be cleaved by the viral protease (PR) during early infection. Characterization of viruses, with amino-acid substitutions that modulate PR cleavage of NC in vitro, was performed in cell culture. Two of the NC mutants, NCN17F and NCN17G,...

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Identifiers

PMID: 16904152
DOI: 10.1016/j.virol.2006.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16904152-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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