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Article

Role of capsid sequence and immature nucleocapsid proteins p9 and p15 in Human Immunodeficiency Virus type 1 genomic RNA dimerization.

Virology - 1 Mar 2009

Kafaie Jafar, Dolatshahi Marjan, Ajamian Lara, Song Rujun, Mouland Andrew J, Rouiller Isabelle, Laughrea Michael

Abstract excerpt

HIV-1 genomic RNA (gRNA) dimerization is important for viral infectivity and is regulated by proteolytic processing of the Gag precursor protein (Pr55gag) under the direction of the viral protease. The processing occurs in successive steps and, to date, the step associated with formation of a wild-type (WT) level of gRNA dimers has not been identified. The primary cleavage divides Pr55gag into two proteins. The...

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Identifiers

PMID: 19070880
DOI: 10.1016/j.virol.2008.11.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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