Article
Incorporation of genetic model parameters for cost-effective designs of genetic association studies using DNA pooling.
BMC genomics - 16 Jul 2007
Ji Fei, Finch Stephen J, Haynes Chad, Mendell Nancy R, Gordon Derek
Abstract excerpt
BACKGROUND: Studies of association methods using DNA pooling of single nucleotide polymorphisms (SNPs) have focused primarily on the effects of "machine-error", number of replicates, and the size of the pool. We use the non-centrality parameter (NCP) for the analysis of variance test to compute t...
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