Article
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
PLoS pathogens - 1 Jul 2007
Eto Danelle S, Jones Tiffani A, Sundsbak Jamie L, Mulvey Matthew A
Abstract excerpt
Uropathogenic Escherichia coli (UPEC), the primary causative agent of urinary tract infections, typically express filamentous adhesive organelles called type 1 pili that mediate both bacterial attachment to and invasion of bladder urothelial cells. Several host proteins have previously been identified as receptors for type 1 pili, but none have been conclusively shown to promote UPEC entry into host bladder...
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