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Article

Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic <i>Escherichia coli</i>

20 Nov 1998

Abstract excerpt

Virtually all uropathogenic strains of Escherichia coli encode filamentous surface adhesive organelles called type 1 pili. High-resolution electron microscopy of infected mouse bladders revealed that type 1 pilus tips interacted directly with the lumenal surface of the bladder, which is embedded with hexagonal arrays of integral membrane glycoproteins known as uroplakins. Attached pili were shortened and...

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PMID: 9822381
DOI: 10.1126/science.282.5393.1494

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