Article
Sticky Fibers and Uropathogenesis: Bacterial Adhesins in the Urinary Tract
1 Jun 2006
Abstract excerpt
Adhesins mediate the introduction of bacteria to the host in the sometimes life-long relationship of uropathogenic Esherichia coli (UPEC) and the human urinary tract. As a class of extracellular proteins, adhesins enable bacteria to adhere to and, in some cases, invade host tissue; adhesins render UPEC virulent and permit host colonization. Adhesin receptor interactions at the host interface determine tissue...
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