Structure and Function ofEscherichia coliType 1 Pili: New Insightinto the Pathogenesis of Urinary Tract Infections

Abstract excerpt

The initial step in the establishment of a mucosal bacterial infection is the interaction of bacterial adhesive proteins with epithelial cells, an event that is often followed by invasion of the epithelial cell. Invasion of host cells has been proposed to provide bacterial pathogens with a means of escaping the harsh extracellular environment, where antibodies, complement, defensins, and other antibacterial...

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