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Article

Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells.

Cellular microbiology - 1 Feb 2006

Wang Beinan, Yurecko Ryan S, Dedhar Shoukat, Cleary P Patrick

Abstract excerpt

Entry of Streptococcus pyogenes or group A streptococcus (GAS) into host cells is mediated by fibronectin bound to surface proteins, M1 or PrtF1, forming a bridge to alpha5beta1 integrins. This interaction leads to cytoskeletal rearrangement and uptake of streptococci. We postulated that integrin-linked kinase (ILK), which directly associates with integrins, is the universal link between integrins and several...

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Share to Adhesins, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacterial Outer Membrane Proteins

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Source

Identifiers

PMID: 16441436
DOI: 10.1111/j.1462-5822.2005.00618.x

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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