Intracellular replication is essential for the virulence of Salmonella typhimurium.

doi:10.1073/pnas.88.24.11470

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Article

Intracellular replication is essential for the virulence of Salmonella typhimurium.

Proceedings of the National Academy of Sciences of the United States of America - 15 Dec 1991

Leung K Y, Finlay B B

Abstract excerpt

Salmonella typhimurium is a facultative intracellular parasite, capable of penetrating, surviving, and multiplying within diverse eukaryotic cell types, including epithelial and phagocytic cells. We have been studying intracellular replication of S. typhimurium and found that it is essential in t...

Topics

Animals
Cell Line
HeLa Cells
Humans
Kinetics
Macrophages
Mice
Mice, Inbred BALB C
Mutagenesis, Insertional
Peritoneal Cavity
Phenotype
Salmonella typhimurium
Virulence

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