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Genetic Determinants of Salmonella enterica Serovar Typhimurium Proliferation in the Cytosol of Epithelial Cells.

Infection and immunity - 1 Dec 2016

Wrande Marie, Andrews-Polymenis Helene, Twedt Donna J, Steele-Mortimer Olivia, Porwollik Steffen, McClelland Michael, Knodler Leigh A

Abstract excerpt

Intestinal epithelial cells provide an important colonization niche for Salmonella enterica serovar Typhimurium during gastrointestinal infections. In infected epithelial cells, a subpopulation of S Typhimurium bacteria damage their internalization vacuole, leading to escape from the Salmonella-containing vacuole (SCV) and extensive proliferation in the cytosol. Little is known about the bacterial determinants of...

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Identifiers

PMID: 27698022
DOI: 10.1128/IAI.00734-16
PMCID: PMC5116728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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