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Article

Mechanisms of HDAC inhibitor-induced thrombocytopenia.

European journal of pharmacology - 1 Oct 2007

Matsuoka Hideaki, Unami Akira, Fujimura Takao, Noto Takahisa, Takata Yoko, Yoshizawa Katsuhiko, Mori Hiroaki, Aramori Ichiro, Mutoh Seitaro

Abstract excerpt

Histone deacetylase inhibitors (HDAC inhibitors) are an emerging class of anticancer agents. To elucidate the mechanism of HDAC inhibitor-induced thrombocytopenia, we focused on the effects of HDAC inhibitors on megakaryocyte differentiation and performed Affymetrix GeneChip analysis of human meg...

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Source

Identifiers

PMID: 17628529
DOI: 10.1016/j.ejphar.2007.06.015

Genes

LMO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17628529-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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