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GATA family transcriptional factors: emerging suspects in hematologic disorders

6 Oct 2015

Abstract excerpt

GATA transcription factors are zinc finger DNA binding proteins that regulate transcription during development and cell differentiation. The three important GATA transcription factors GATA1, GATA2 and GATA3 play essential roles in the development and maintenance of hematopoietic systems. GATA1 is required for the erythroid and megakaryocytic commitment during hematopoiesis. GATA2 is crucial for the proliferation...

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PMID: 26445707
DOI: 10.1186/s40164-015-0024-z

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