Article
GATA transcription factors and hematological diseases.
The Tohoku journal of experimental medicine - 1 Sept 2006
Harigae Hideo
Abstract excerpt
The development of mature blood cells from hematopoietic stem cells is regulated by transcription factors that control and coordinate the expression of lineage-specific genes. The GATA family consists of six transcription factors that function in hematopoietic and endodermal development. Among them, GATA-1 is expressed in erythroid, megakaryocytic, eosinophil and mast cell lineages, and GATA-2 is expressed in...
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