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Article

Expression Levels of Histone Deacetylases Determine the Cell Fate of Hematopoietic Progenitors

8 Sept 2009

Abstract excerpt

Histone deacetylases (HDACs) are globally implicated in the growth and differentiation of mammalian cells; however, relatively little is known about their specific roles in hematopoiesis. In this study, we investigated the expression of HDACs in human hematopoietic cells and their functions during hematopoiesis. The expression of HDACs was very low in hematopoietic progenitor cells, which was accompanied by...

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PMID: 19736310
DOI: 10.1074/jbc.m109.042242

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