Article
Human population genetic structure and inference of group membership.
American journal of human genetics - 1 Mar 2003
Bamshad Michael J, Wooding Stephen, Watkins W Scott, Ostler Christopher T, Batzer Mark A, Jorde Lynn B
Abstract excerpt
A major goal of biomedical research is to develop the capability to provide highly personalized health care. To do so, it is necessary to understand the distribution of interindividual genetic variation at loci underlying physical characteristics, disease susceptibility, and response to treatment. Variation at these loci commonly exhibits geographic structuring and may contribute to phenotypic differences between...
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