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Article

Human genetic variation studies and HLA class II loci.

International journal of immunogenetics - 1 Aug 2007

Agrawal S, Khan F, Bharadwaj U

Abstract excerpt

Human leucocyte antigen (HLA) loci widely known for their role in generation of immune responses by encoding cell-surface heterodimers are often considered to be effective for the purpose of reconstructing human phylogenies due to high degree of polymorphism and less recombination. In the present study, we have made an attempt to study HLA class II loci (DRB1, DQA1 and DQB1) in inferring phylogenetic relationship...

Topics

Alleles
Gene Frequency
Genes, MHC Class II
Genetic Variation
Haplotypes
Humans
Phylogeny
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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 17627759
DOI: 10.1111/j.1744-313X.2007.00683.x

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