Article
Distinctive KIR and HLA diversity in a panel of north Indian Hindus.
Immunogenetics - 1 Mar 2002
Rajalingam Raja, Krausa Peter, Shilling Heather G, Stein Jason B, Balamurugan Arumugam, McGinnis Malcolm D, Cheng Nathalie W, Mehra Narinder K, Parham Peter
Abstract excerpt
HLA and KIR are diverse and rapidly evolving gene complexes that work together in human immunity mediated by cytolytic lymphocytes. Understanding their complex immunogenetic interaction requires study of both HLA and KIR diversity in the same human population. Here a panel of 72 unrelated north Indian Hindus was analyzed. HLA- A, B, C, DRB1, DQA1, and DQB1 alleles and their frequencies were determined by...
Topics
- Alleles
- Ethnicity
- Gene Frequency
- Genetic Variation
- HLA Antigens
- HLA-A Antigens
- HLA-A2 Antigen
- HLA-B Antigens
- HLA-C Antigens
- Haplotypes
- Humans
- India
- Receptors, Immunologic
- Receptors, KIR
- Receptors, KIR2DL1
