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Article

Persistence of rRNA operon mutated copies and rapid re-emergence of linezolid resistance in Staphylococcus aureus.

The Journal of antimicrobial chemotherapy - 1 Sept 2007

Tsakris Athanassios, Pillai Satish K, Gold Howard S, Thauvin-Eliopoulos Claudie, Venkataraman Lata, Wennersten Christine, Moellering Robert C, Eliopoulos George M

Abstract excerpt

OBJECTIVES: The G2576T mutation in domain V of 23S rRNA has been most often associated with the rare cases of linezolid resistance in Staphylococcus aureus. In a linezolid-susceptible S. aureus (A8761B) possessing a single mutated (G2576T) copy, originally derived from a resistant clinical isolat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Ribosomal, 23S

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Source

Identifiers

PMID: 17623697
DOI: 10.1093/jac/dkm246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17623697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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