Article
Komagataella phaffii Encodes Two Functional Pho4 Transcription Factors.
International journal of molecular sciences - 23 Jul 2026
Albacar Marcel, González Asier, Wang Rui, Casamayor Antonio, Ariño Joaquín
Abstract excerpt
The transcription factor Pho4 is crucial for the response to phosphate starvation in many fungi, and it has been linked to tolerance to alkalinization of the medium and to pathogenicity. It is widely accepted that it is encoded by a single gene. However, the industrially relevant yeast Komagataella phaffii might contain two Pho4-encoding genes (PAS_chr1-1_0265 and PAS_chr2-1_0177, designated here PHO4(A) and...
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