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Article

Cross‐talk of global nutritional regulators in the control of primary and secondary metabolism in Streptomyces

19 Dec 2010

Abstract excerpt

Limitation of different nutrients in Streptomyces coelicolor A3(2) triggers nutrient-stress responses, mediated by PhoP, GlnR, AfsR and other regulators, that are integrated at the molecular level and control secondary metabolite biosynthesis and differentiation. In addition, utilization of chitin or N-acetylglucosamine regulates secondary metabolite biosynthesis by a mechanism mediated by DasR. Phosphate control...

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PMID: 21342462
DOI: 10.1111/j.1751-7915.2010.00235.x

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Cross‐talk of global nutritional regulators in the control of primary and secondary metabolism in StreptomycesPMID 21342462Read ↗

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The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development.Semantic proximity Read ↗

Diverse control of metabolism and other cellular processes in Streptomyces coelicolor by the PhoP transcription factor: genome-wide identification of in vivo targetsSemantic proximity Read ↗

Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor.Semantic proximity Read ↗

Characterization of a new GlnR binding box in the promoter of amtB in Streptomyces coelicolor inferred a PhoP/GlnR competitive binding mechanism for transcriptional regulation of amtB.Semantic proximity Read ↗

Intertwining nutrient‐sensory networks and the control of antibiotic production in<i>Streptomyces</i>Semantic proximity Read ↗

Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2).Semantic proximity Read ↗

Molecular Mechanisms of Phosphate Sensing, Transport and Signalling in Streptomyces and Related ActinobacteriaSemantic proximity Read ↗

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The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria.Semantic proximity Read ↗

Two transcriptional regulators GlnR and GlnRII are involved in regulation of nitrogen metabolism in Streptomyces coelicolor A3(2)Semantic proximity Read ↗

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