Article
Is PhoR-PhoP partner fidelity strict? PhoR is required for the activation of the pho regulon in Streptomyces coelicolor.
Molecular genetics and genomics : MGG - 1 Jul 2012
Fernández-Martínez Lorena T, Santos-Beneit Fernando, Martín Juan F
Abstract excerpt
Two-component regulatory systems play a key role in the cell metabolism adaptation to changing nutritional and environmental conditions. The fidelity between the two cognate proteins of a two-component system is important since it determines whether a specific response regulator integrates the signals transmitted by different sensor kinases. Phosphate regulation in Streptomyces coelicolor is mostly mediated by...
Topics
- Anthraquinones
- Bacterial Proteins
- Gene Expression Regulation, Bacterial
- Histidine Kinase
- Mutation
- Operon
- Phosphates
- Phosphorylation
- Promoter Regions, Genetic
- Protein Kinases
- Regulon
- Reverse Transcriptase Polymerase Chain Reaction
- Streptomyces coelicolor
- Time Factors
- Transcription Factors