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Article

A structural split in the human genome.

PloS one - 11 Jul 2007

Tang Clara S M, Epstein Richard J

Abstract excerpt

BACKGROUND: Promoter-associated CpG islands (PCIs) mediate methylation-dependent gene silencing, yet tend to co-locate to transcriptionally active genes. To address this paradox, we used data mining to assess the behavior of PCI-positive (PCI+) genes in the human genome. RESULTS: PCI+ genes exhib...

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Identifiers

PMID: 17622348
DOI: 10.1371/journal.pone.0000603
PMCID: PMC1904255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17622348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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