Article
Evaluation of tafazzin as candidate for dilated cardiomyopathy in Irish wolfhounds.
The Journal of heredity - 1 Jan 2007
Philipp Ute, Broschk Cornelia, Vollmar Andrea, Distl Ottmar
Abstract excerpt
Dilated cardiomyopathy (DCM) is a common disease in humans and dogs. Large-breed dogs and especially Irish wolfhounds belong to the frequently affected breeds. Male Irish wolfhounds show a significantly higher prevalence of DCM than females. Therefore, we evaluated X chromosome markers for linkage with DCM as well as a human candidate gene on the X chromosome. A set of X chromosomal microsatellites was genotyped...
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