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Article

Multiple Loci are associated with dilated cardiomyopathy in Irish wolfhounds.

PloS one - 1 Jan 2012

Philipp Ute, Vollmar Andrea, Häggström Jens, Thomas Anne, Distl Ottmar

Abstract excerpt

Dilated cardiomyopathy (DCM) is a highly prevalent and often lethal disease in Irish wolfhounds. Complex segregation analysis indicated different loci involved in pathogenesis. Linear fixed and mixed models were used for the genome-wide association study. Using 106 DCM cases and 84 controls we identified one SNP significantly associated with DCM on CFA37 and five SNPs suggestively associated with DCM on CFA1, 10,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22761652
DOI: 10.1371/journal.pone.0036691
PMCID: PMC3382626

Genes

ACSL3
MOGAT1

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