Article
Canine candidate genes for dilated cardiomyopathy: annotation of and polymorphic markers for 14 genes.
BMC veterinary research - 19 Oct 2007
Wiersma Anje C, Leegwater Peter Aj, van Oost Bernard A, Ollier William E, Dukes-McEwan Joanna
Abstract excerpt
BACKGROUND: Dilated cardiomyopathy is a myocardial disease occurring in humans and domestic animals and is characterized by dilatation of the left ventricle, reduced systolic function and increased sphericity of the left ventricle. Dilated cardiomyopathy has been observed in several, mostly large and giant, dog breeds, such as the Dobermann and the Great Dane. A number of genes have been identified, which are...
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