Article
Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy.
BioMed research international - 1 Jan 2016
Simpson Siobhan, Dunning Mark D, Brownlie Serena, Patel Janika, Godden Megan, Cobb Malcolm, Mongan Nigel P, Rutland Catrin S
Abstract excerpt
Cardiac disease is a leading cause of morbidity and mortality in dogs and humans, with dilated cardiomyopathy being a large contributor to this. The Irish Wolfhound (IWH) is one of the most commonly affected breeds and one of the few breeds with genetic loci associated with the disease. Mutations in more than 50 genes are associated with human dilated cardiomyopathy (DCM), yet very few are also associated with...
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