Article
Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia.
Journal of hypertension - 1 Aug 2007
Carnicer Ricardo, Navarro María A, Arbonés-Mainar José M, Arnal Carmen, Surra Joaquín C, Acín Sergio, Sarría Alfonso, Blanco-Vaca Francisco, Maeda Nobuyo, Osada Jesús
Abstract excerpt
BACKGROUND: Hyperhomocysteinemia and hypoalphalipoproteinemia are two well-reported risk factors for cardiovascular disease. The effects of the synergistic combination of these two factors on vascular function need to be investigated. METHODS AND RESULTS: Four groups of male mice were used: a control wild-type group; a group of mice heterozygous for cystathionine beta-synthase deficiency; a group of mice...
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