Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development.

The Journal of cell biology - 16 Jul 2007

Koh Tong-Wey, Korolchuk Viktor I, Wairkar Yogesh P, Jiao Wei, Evergren Emma, Pan Hongling, Zhou Yi, Venken Koen J T, Shupliakov Oleg, Robinson Iain M, O'Kane Cahir J, Bellen Hugo J

Abstract excerpt

Epidermal growth factor receptor pathway substrate clone 15 (Eps15) is a protein implicated in endocytosis, endosomal protein sorting, and cytoskeletal organization. Its role is, however, still unclear, because of reasons including limitations of dominant-negative experiments and apparent redundancy with other endocytic proteins. We generated Drosophila eps15-null mutants and show that Eps15 is required for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endocytosis

Share to Nerve Tissue Proteins

Share to Synapses

Share to Synaptic Vesicles

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17620409
DOI: 10.1083/jcb.200701030
PMCID: PMC2064449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development.PMID 17620409Read ↗

Drosophila homologue of Eps15 is essential for synaptic vesicle recycling.Semantic proximity Read ↗

Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth.Semantic proximity Read ↗

Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis.Semantic proximity Read ↗

The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling.Semantic proximity Read ↗

Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.Semantic proximity Read ↗

Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.Semantic proximity Read ↗

Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components.Semantic proximity Read ↗

Drosophila liquid facets-Related encodes Golgi epsin and is an essential gene required for cell proliferation, growth, and patterning.Semantic proximity Read ↗

Inhibition of clathrin-coated pit assembly by an Eps15 mutant.Semantic proximity Read ↗

Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis.Semantic proximity Read ↗

Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins.Semantic proximity Read ↗

Endocytosis restricts dendrite branching via removing ectopically localized branching ligands.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.