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Article

Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis.

Neuron - 22 Jul 2004

Koh Tong-Wey, Verstreken Patrik, Bellen Hugo J

Abstract excerpt

We describe the isolation of mutations in dynamin-associated protein 160 kDa (dap160), the Drosophila homolog of intersectin, a putative adaptor for proteins involved in endocytosis, cytoskeletal regulation, and signaling. We show that partial loss-of-function mutants display temperature-sensitive (ts) paralysis, whereas null mutants show ts defects in endocytosis. Loss-of-function mutants exhibit bouton...

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Identifiers

PMID: 15260956
DOI: 10.1016/j.neuron.2004.06.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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