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Article

Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR.

Toxicology - 5 Sept 2007

Lee Chul-Ho, Ito Yuki, Yanagiba Yukie, Yamanoshita Osamu, Kim Heon, Zhang Shu-Yun, Kamijima Michihiro, Gonzalez Frank J, Nakajima Tamie

Abstract excerpt

Aryl hydrocarbon receptor (AhR) plays important roles in the regulation and induction of xenobiotic-metabolizing enzymes including the cytochromes P450 1 family (CYP1) and UDP-glucuronosyltransferases 1A (UGT1As) by polycyclic aromatic hydrocarbons as well as chlorinated aromatic hydrocarbons. To determine whether pyrene-induced xenobiotic-metabolizing enzymes are regulated by AhR, male AhR (+/+) and (-/-) mice...

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Identifiers

PMID: 17618724
DOI: 10.1016/j.tox.2007.05.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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