Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.

BMC medical genetics - 7 Jul 2007

Bouatia-Naji Nabila, Vatin Vincent, Lecoeur Cécile, Heude Barbara, Proença Christine, Veslot Jacques, Jouret Béatrice, Tichet Jean, Charpentier Guillaume, Marre Michel, Balkau Beverley, Froguel Philippe, Meyre David

Abstract excerpt

BACKGROUND: 7B2 is a regulator/activator of the prohormone convertase 2 which is involved in the processing of numerous neuropeptides, including insulin, glucagon and pro-opiomelanocortin. We have previously described a suggestive genetic linkage peak with childhood obesity on chr15q12-q14, where the 7B2 encoding gene, SGNE1 is located. The aim of this study is to analyze associations of SGNE1 genetic variation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to France

Share to Glucose Intolerance

Share to Insulin Resistance

Share to Obesity

Source

Open in PubMed Open full text

Identifiers

PMID: 17617923
DOI: 10.1186/1471-2350-8-44
PMCID: PMC1936990

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.PMID 17617923Read ↗

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.Semantic proximity Read ↗

Identifying Genetic Factors Contributing to Non-Syndromic Early-Onset Childhood Obesity Utilizing Whole-Exome Sequencing in Consanguineous Families.Semantic proximity Read ↗

Genetic risk profiles for a childhood with severe overweight.Semantic proximity Read ↗

Clinical phenotypes of adults with monogenic and syndromic genetic obesity.Semantic proximity Read ↗

Investigating genetic variants in early-onset obesity through exome sequencing: A retrospective cohort study.Semantic proximity Read ↗

Associations Between Type 2 Diabetes-Related Genetic Scores and Metabolic Traits, in Obese and Normal-Weight Youths.Semantic proximity Read ↗

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.Semantic proximity Read ↗

Studies of metabolic phenotypic correlates of 15 obesity associated gene variants.Semantic proximity Read ↗

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.Semantic proximity Read ↗

Validation of obesity susceptibility loci identified by genome-wide association studies in early childhood in South Brazilian children.Semantic proximity Read ↗

Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants.Semantic proximity Read ↗

Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.