Article
The p73 polymorphisms are not associated with susceptibility to esophageal squamous cell carcinoma in a high incidence region of China.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2007
Ge H, Wang Y-M, Cao Y-Y, Chen Z-F, Wen D-G, Guo W, Wang N, Zhang X-F, Li Y, Zhang J-H
Abstract excerpt
P73, a p53 homolog, has some p53-like activities and plays an important role in modulating cell cycle, apoptosis and DNA repair. The two linked polymorphisms in the non-coding region of exon2 of p73 gene, named G4C14-A4T14, may alter translation efficiency of the gene. The transcription of p73 ge...
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