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Article

[Correlation of 53BP1 and p53 polymorphisms to susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma].

Ai zheng = Aizheng = Chinese journal of cancer - 1 Oct 2007

Cao Yan-Yan, Ge Hui, Chen Long-Qi, Chen Zhi-Feng, Wen Deng-Gui, Li Yan, Zhang Jian-Hui

Abstract excerpt

BACKGROUND & OBJECTIVE: 53BP1 is one of p53-binding proteins, which can enhance the transcriptional activation of p53 and plays a key role in tumor suppression. A single nucleotide polymorphism (SNP) T885G has been found in the promoter of 53BP1. This study was to investigate the correlation of 53BP1 and p53 SNPs to susceptibility to esophageal squamous cell carcinoma (ESCC) and gastric cardiac adenocarcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17927872

Genes

GCA

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