Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.

Cancer research - 1 Jul 2007

Paulson K Eric, Rieger-Christ Kimberly, McDevitt Michael A, Kuperwasser Charlotte, Kim Jiyoung, Unanue Vincent E, Zhang Xiaowei, Hu Maowen, Ruthazer Robin, Berasi Stephen P, Huang Chun-Yin, Giri Dilip, Kaufman Seth, Dugan John M, Blum Joanne, Netto Georges, Wazer David E, Summerhayes Ian C, Yee Amy S

Abstract excerpt

Invasive breast cancer has a high risk of recurrence to incurable disease and needs improved prognostic and therapeutic tools. Our work combines clinical and molecular analyses to show that the transcriptional repressor HBP1 may be a new target for invasive breast cancer. Previous work indicated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Neoplastic
Share to High Mobility Group Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, SCID

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to Neoplasm Transplantation

Share to NIH 3T3 Cells

Share to Repressor Proteins

Source

Identifiers

PMID: 17616670
DOI: 10.1158/0008-5472.CAN-07-0567

Genes

HBP1
SFRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17616670-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.PMID 17616670Read ↗

Suppression of Wnt Signaling by the Green Tea Compound (–)-Epigallocatechin 3-Gallate (EGCG) in Invasive Breast Cancer CellsSemantic proximity Read ↗

The role of YY1 in reduced HP1alpha gene expression in invasive human breast cancer cells.Semantic proximity Read ↗

Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesisSemantic proximity Read ↗

A Placenta-Specific Gene Ectopically Activated in Many Human Cancers Is Essentially Involved in Malignant Cell ProcessesSemantic proximity Read ↗

The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature SenescenceSemantic proximity Read ↗

Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype.Semantic proximity Read ↗

The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.Semantic proximity Read ↗

Epigenetic silencing of HOPX contributes to cancer aggressiveness in breast cancer.Semantic proximity Read ↗

Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells.Semantic proximity Read ↗

Dysregulated protease activated receptor 1 (PAR1) promotes metastatic phenotype in breast cancer through HMGA2.Semantic proximity Read ↗

Down-regulation of HP1Hsalpha expression is associated with the metastatic phenotype in breast cancer.Semantic proximity Read ↗

HOPX Is an Epigenetically Inactivated Tumor Suppressor and Overexpression of HOPX Induce Apoptosis and Cell Cycle Arrest in Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.