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Article

Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer.

Cancer research - 1 Jul 2007

Paulson K Eric, Rieger-Christ Kimberly, McDevitt Michael A, Kuperwasser Charlotte, Kim Jiyoung, Unanue Vincent E, Zhang Xiaowei, Hu Maowen, Ruthazer Robin, Berasi Stephen P, Huang Chun-Yin, Giri Dilip, Kaufman Seth, Dugan John M, Blum Joanne, Netto Georges, Wazer David E, Summerhayes Ian C, Yee Amy S

Abstract excerpt

Invasive breast cancer has a high risk of recurrence to incurable disease and needs improved prognostic and therapeutic tools. Our work combines clinical and molecular analyses to show that the transcriptional repressor HBP1 may be a new target for invasive breast cancer. Previous work indicated that HBP1 regulated proliferation and senescence and inhibited Wnt signaling. Two of these functions have been...

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Identifiers

PMID: 17616670
DOI: 10.1158/0008-5472.CAN-07-0567

Genes

HBP1
SFRP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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