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Article

The tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.

The Journal of biological chemistry - 12 Feb 2010

Escamilla-Powers Julienne R, Daniel Colin J, Farrell Amy, Taylor Karyn, Zhang Xiaoli, Byers Sarah, Sears Rosalie

Abstract excerpt

c-Myc is an important transcription factor that regulates cellular proliferation, cell growth, and differentiation. A number of transcriptional co-factors for c-Myc have been described that have binding sites within highly conserved regions of the c-Myc transactivational domain (TAD). Given the i...

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Source

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Identifiers

PMID: 20008325
DOI: 10.1074/jbc.M109.074856
PMCID: PMC2836090

Genes

HBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20008325-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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