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Article

Functional polymorphisms of the cytochrome P450 1A2 (CYP1A2) gene and prolonged QTc interval in schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Aug 2007

Tay Joshua K X, Tan Chay Hoon, Chong Siow-Ann, Tan Ene-Choo

Abstract excerpt

CYP1A2 is an important inducible enzyme involved in the metabolism of antipsychotics. This study examined two functional polymorphisms in the gene as potential markers in predicting prolongation of QTc interval in patients treated with antipsychotics. QT intervals were measured by 12-lead electro...

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Source

Identifiers

PMID: 17611010
DOI: 10.1016/j.pnpbp.2007.05.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17611010-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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