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Article

Electrocardiogram Alterations Associated With Psychotropic Drug Use and CACNA1C Gene Variants in Three Independent Samples.

Basic & clinical pharmacology & toxicology - 1 May 2017

Fabbri Chiara, Boriani Giuseppe, Diemberger Igor, Filippi Maria Giulia, Ravegnini Gloria, Hrelia Patrizia, Minarini Alessandro, Albani Diego, Forloni Gianluigi, Angelini Sabrina, Serretti Alessandro

Abstract excerpt

Several antipsychotics and antidepressants have been associated with QTc prolongation or other electrocardiogram (ECG) alterations, but their impact is still debated and other risk factors are known to affect QTc. We investigated the effect of antidepressants and antipsychotics on QTc and other ECG intervals/waves in three samples. Two discovery samples (cross-sectional sample n = 145 and prospective sample n =...

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Identifiers

PMID: 27893184
DOI: 10.1111/bcpt.12720

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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