Article
Genetic Biomarkers of Antipsychotic-Induced Prolongation of the QT Interval in Patients with Schizophrenia.
International journal of molecular sciences - 13 Dec 2022
Vaiman Elena E, Shnayder Natalia A, Zhuravlev Nikita M, Petrova Marina M, Asadullin Azat R, Al-Zamil Mustafa, Garganeeva Natalia P, Shipulin German A, Cumming Paul, Nasyrova Regina F
Abstract excerpt
Antipsychotics (AP) induced prolongation of the QT interval in patients with schizophrenia (Sch) is an actual interdisciplinary problem as it increases the risk of sudden death syndrome. Long QT syndrome (LQTS) as a cardiac adverse drug reaction is a multifactorial symptomatic disorder, the development of which is influenced by modifying factors (APs' dose, duration of APs therapy, APs polytherapy, and...
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