Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention

16 Apr 2014

Abstract excerpt

Signal Transducers and Activators of Transcription (STATs) are a family of transcription factors that regulate cell proliferation, differentiation, apoptosis, immune and inflammatory responses, and angiogenesis. Cumulative evidence has established that STAT3 has a critical role in the development of multiple cancer types. Because it is constitutively activated during disease progression and metastasis in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cytokine Signaling Pathways and Interactions
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24743778
DOI: 10.3390/cancers6020926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription Factor STAT3 as a Novel Molecular Target for Cancer PreventionPMID 24743778Read ↗

Critical analysis of the potential for targeting STAT3 in human malignancySemantic proximity Read ↗

STAT3 Signaling in CancerSemantic proximity Read ↗

STAT3 SIGNALING: Anticancer Strategies and ChallengesSemantic proximity Read ↗

STAT3 Target Genes Relevant to Human CancersSemantic proximity Read ↗

Novel activators and small-molecule inhibitors of STAT3 in cancerSemantic proximity Read ↗

STAT3: A Potential Drug Target for Tumor and InflammationSemantic proximity Read ↗

Overview of the STAT‑3 signaling pathway in cancer and the development of specific inhibitors (Review)Semantic proximity Read ↗

Oncogenic STAT Transcription Factors as Targets for Cancer Therapy: Innovative Strategies and Clinical TranslationSemantic proximity Read ↗

Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discoverySemantic proximity Read ↗

Signal Transducers and Activators of Transcription (STATs): Novel Targets of Chemopreventive and Chemotherapeutic DrugsSemantic proximity Read ↗

The potential and controversy of targeting STAT family members in cancerSemantic proximity Read ↗

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.