Article
Genotypic resistance tests in the management of the HIV-infected patient at virological failure.
Scandinavian journal of infectious diseases. Supplementum - 1 Jan 2003
Aceti Antonio, Carosi Giampiero
Abstract excerpt
Witness for the prosecution: The IAS-USA and Euro-Resistance Group HIV guidelines recommend the use of resistance testing for all patients experiencing treatment failure for whom therapy change is being considered. However, these assays suffer from several limitations (problems in sensitivity, specificity, complexity of interpretation, cost) and the results of the prospective studies evaluating genotype-guided...
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