Article
Phenotype of bone metastases of non-small cell lung cancer: epidermal growth factor receptor expression and K-RAS mutational status.
Pathology oncology research : POR - 1 Jan 2007
Badalian Gayane, Barbai Tamás, Rásó Erzsébet, Derecskei Katalin, Szendrôi Miklós, Tímár József
Abstract excerpt
Bone metastasis is a frequent complication of lung cancer progression, however, studies on bone metastatic tissues are scanty. Here we have collected a small cohort of 11 non-small cell lung cancer cases where primary tumors and corresponding bone metastases were available for pathological analysis. We have tested two molecular markers: EGFR protein expression and K-RAS mutation at codon 12 using...
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