Association of mutation profiles with metastasis in patients with non-small cell lung cancer

Abstract excerpt

Objective: This study focused on the analysis of the correlation between common gene mutation types and metastatic sites in NSCLC patients. Methods: We retrospectively studied 1586 NSCLC patients and used fluorescence Polymerase chain reaction (PCR) to detect EGFR, ALK, ROS1, RET, MET, BRAF, HER2, KRAS, NRAS, and PIK3CA gene mutations, and also investigated sex, smoking status, age at diagnosis, histological type...

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