Article
EGFR mutated non-small cell lung cancer patients: more prone to development of bone and brain metastases?
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2014
Hendriks L E L, Smit E F, Vosse B A H, Mellema W W, Heideman D A M, Bootsma G P, Westenend M, Pitz C, de Vries G J, Houben R, Grünberg K, Bendek M, Speel E-J M, Dingemans A-M C
Abstract excerpt
OBJECTIVES: Both bone and brain are frequent sites of metastasis in non-small cell lung cancer (NSCLC). Conflicting data exist whether EGFR mutant (+) patients are more prone to develop brain metastases or have a better outcome with brain metastases compared to EGFR/KRAS wildtype (WT) or KRAS+ patients. For bone metastases this has not been studied. METHODS: In this retrospective case-control study all EGFR+...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.