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Article

Features and prognostic impact of distant metastasis in patients with stage IV lung adenocarcinoma harboring EGFR mutations: importance of bone metastasis.

Clinical & experimental metastasis - 1 Jun 2014

Fujimoto Daichi, Ueda Hiroyuki, Shimizu Ryoko, Kato Ryoji, Otoshi Takehiro, Kawamura Takahisa, Tamai Koji, Shibata Yumi, Matsumoto Takeshi, Nagata Kazuma, Otsuka Kyoko, Nakagawa Atsushi, Otsuka Kojiro, Katakami Nobuyuki, Tomii Keisuke

Abstract excerpt

Mutated epidermal growth factor receptor (EGFR) and signaling pathways were associated with multiple brain and intra-pulmonary metastases, oncogenic progression and metastasis. However, features of metastasis to other organs and the independent prognostic influence of metastatic lesions were not elucidated in patients with lung cancer harboring EGFR mutations. Between January 2007 and April 2012, we treated 277...

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Identifiers

PMID: 24682604
DOI: 10.1007/s10585-014-9648-3

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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